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Evidence-Based Toxicology Collaboration


Publications

A systematic review to compare chemical hazard predictions of the zebrafish embryotoxicity test with mammalian prenatal developmental toxicity

Sebastian Hoffmann, Bianca Marigliani, Sevcan Gül Akgün-Ölmez, Danielle Ireland, Rebecca Cruz, Francois Busquet, Burkhard Flick, Manoj Lalu, Elizabeth C Ghandakly, Rob B M de Vries, Hilda Witters, Robert A Wright, Metin Ölmez, Catherine Willett, Thomas Hartung, Martin L Stephens, Katya Tsaioun. Toxicological Sciences, 09 June 2021
https://doi.org/10.1093/toxsci/kfab072


Applying evidence-based methods to the development and use of adverse outcome pathways

de Vries, R. B. M., Angrish, M., Browne, P., Brozek, J., Rooney, A. A., Wikoff, D. S., Whaley, P., Edwards, S. W., Morgan, R. L., Druwe, I. L., Hoffmann, S., Hartung, T., Thayer, K., Avey, M. T., Beverly, B. E. J., Falavigna, M., Gibbons, C., Goyak, K., Kraft, A., Nampo, F., Qaseem, A., Sears, M., Singh, J. A., Willett, C., Yost, E. Y. ., Schünemann, H. and Tsaioun, K. ALTEX—Alternatives to animal experimentation, 38(2), pp. 336-347.
https://www.altex.org/index.php/altex/article/view/2248


Performance of preclinical models in predicting drug-induced liver injury in humans: a systematic review

Hubert Dirven, Gunn E. Vist, Sricharan Bandhakavi, Jyotsna Mehta, Seneca E. Fitch, Pandora Pound, Rebecca Ram, Breanne Kincaid, Cathalijn H. C. Leenaars, Minjun Chen, Robert A. Wright, Katya Tsaioun. Scientific Reports volume 11, Article number: 6403 (2021)
https://doi.org/10.1038/s41598-021-85708-2


Knowledge organization systems for systematic chemical assessments

Paul Whaley, Stephen W. Edwards, Andrew Kraft, Kate Nyhan, Andrew Shapiro, Sean Watford, Steven Wattam, Taylor Wolffe, and Michelle Angrish. Environmental Health Perspectives, Volume 128, No. 12, December 2020.
https://ehp.niehs.nih.gov/doi/full/10.1289/EHP6994


Reviewing the animal literature: how to describe and choose between different types of literature reviews

Cathalign Leenaars, Katya Tsaioun, Frans Stafleu, Kieron Rooney, Franck Meiboom, Merel Ritskes-Hoitinga, Andre Bleich
pubmed.gov, November 2020
https://pubmed.ncbi.nlm.nih.gov/33135562/


Artificial Intelligence for chemical risk assessment

Clemens Wittwehr, Paul Blomstedt, John Paul Gosling, Tomi Peltola, Barbara Raffael, Andrea-Nicole Richarz, Marta Sienkiewicz, Paul Whaley, Andrew Worth, Maurice Whelan. Computational Toxicology, Volume 13, 2020, 100114, ISSN 2468-1113.
https://doi.org/10.1016/j.comtox.2019.100114


A survey of systematic evidence mapping practice and the case for knowledge graphs in environmental health and toxicology

Taylor A M Wolffe, John Vidler, Crispin Halsall, Neil Hunt, Paul Whaley. Toxicological Sciences, Volume 175, Issue 1, May 2020, Pages 35–49,
https://doi.org/10.1093/toxsci/kfaa025


Recommendations for the conduct of systematic reviews in toxicology and environmental health research (COSTER)

Paul Whaley, Elisa Aiassa, Claire Beausoleil, Anna Beronius, Gary Bilotta, Alan Boobis, Rob de Vries, Annika Hanberg, Sebastian Hoffmann, Neil Hunt, Carol F. Kwiatkowski, Juleen Lam, Steven Lipworth, Olwenn Martin, Nicola Randall, Lorenz Rhomberg, Andrew A. Rooney, Holger J. Schünemann, Daniele Wikoff, Taylor Wolffe, Crispin Halsall. Environment International, Volume 143, 2020, 105926, ISSN 0160-4120.
https://doi.org/10.1016/j.envint.2020.105926.


Establishing a health-based recommended occupational exposure limit for nitrous oxide using experimental animal data—A systematic review protocol

Judith A.K.R. van Luijk, Madaline Popa, Janne Swinkels, Julia M.L. Menon, Wynad Alkema, Nel Roeleveld, Sebastian E. Hoffmann, Vivi Schlunssen, Daniele Mandrioli, Merel Ritskes-Hoitinga, Paul T.J. Scheepers. Environmental Research, Volume 178, November 2019, 108711. 
https://www.sciencedirect.com/science/article/pii/S0013935119305080


Systematic evidence maps as a novel tool to support evidence-based decision-making in chemicals policy and risk management

Taylor A.M. Wolffe, Paul Whaley, Crispin Halsall, Andrew A.Rooney, Vickie R.Walker
Environment International, Volume 130, September 2019, 104871. 
https://doi.org/10.1016/j.envint.2019.05.065


Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test 

Martin L Stephens, Sevcan Gül Akgün-Ölmez, Sebastian Hoffmann, Rob de Vries, Burkhard Flick, Thomas Hartung, Manoj Lalu, Alexandra Maertens, Hilda Witters, Robert Wright, Katya Tsaioun. Toxicological Sciences, June 16, 2019. 
https://doi.org/10.1093/toxsci/kfz128


Software tools for literature screening in systematic reviews in biomedical research 

Stevie van der Mierden, Katya Tsaioun, André Bleich, Cathalijn H. C. Leenaars (2019)ALTEX—Alternatives to animal experimentation. doi: 10.14573/altex.1902131. 
https://www.altex.org/index.php/altex/article/view/1257


Toward Good In Vitro Reporting Standards 

Hartung, Thomas, de Vries, Rob, Hoffmann, Sebastian, Hogberg, Helena T., Smirnova, Lena, Tsaioun, Katya, Whaley, Paul Alexander, Leist, Marcel (2019). ALTEX—Alternatives to Animal Experimentation, 36 (1). pp. 3-17. ISSN 1868-8551.
https://doi.org/10.14573/altex.1812191


Evidence integration in risk assessment: the science of combining apples and oranges

European Food Safety Authority
https://doi.org/10.2903/sp.efsa.2018.EN-1396


A primer on systematic reviews in toxicology

Hoffmann, S., de Vries, R.B.M., Stephens, M.L. et al. Arch Toxicol 91, 2551–2575 (2017).
https://doi.org/10.1007/s00204-017-1980-3


The Emergence of Systematic Review in Toxicology

Stephens ML, Betts K, Beck NB, Cogliano V, Dickersin K, Fitzpatrick S, Freeman J, Gray G, Hartung T, McPartland J, Rooney AA, Scherer RW, Verloo D, Hoffmann S. Toxicol Sci. 2016 Jul;152 (1):10-6.
https://doi.org/10.1093/toxsci/kfw059


Evidence-Based Toxicology

Hoffmann S, Hartung T, Stephens M. Adv Exp Med Biol. 2016;856:231-241.
https://link.springer.com/chapter/10.1007%2F978-3-319-33826-2_9


Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review

Samuel GO, Hoffmann S, Wright RA, Lalu MM, Patlewicz G, Becker RA, DeGeorge GL, Fergusson D, Hartung T, Lewis RJ, Stephens ML. Environ Int. 2016 Jul-Aug;92-93:630-46. 
doi: 10.1016/j.envint.2016.03.010


Evidence-Based Toxicology

Reference Module in Biomedical Sciences. 
Encyclopedia of Toxicology (Third Edition), 2014


Evidence-based toxicology for the 21st century: Opportunities and challenges

Stephens ML, Andersen M, Becker RA, Betts K, Boekelheide K, Carney E, Chapin R, Devlin D, Fitzpatrick S, Fowle JR 3rd, Harlow P, Hartung T, Hoffmann S, Holsapple M, Jacobs A, Judson R, Naidenko O, Pastoor T, Patlewicz G, Rowan A, Scherer R, Shaikh R, Simon T, Wolf D, Zurlo J. ALTEX. 2013;30(1):74-103.
doi: 10.14573/altex.2013.1.074


Food for thought… on evidence-based toxicology 

Hartung T. ALTEX. 2009;26(2):75-82.
doi: 10.14573/altex.2009.2.75.


Toward an evidence-based toxicology

Hoffmann S, Hartung T. Hum Exp Toxicol. 2006 Sep;25(9):497-513.
doi: 10.1191/0960327106het648oa.


Diagnosis: toxic!—Trying to apply approaches of clinical diagnostics and prevalence in toxicological considerations

Sebastian Hoffmann, Thomas Hartung. Toxicological Sciences, Volume 85, Issue 1, May 2005, Pages 422–428
https://doi.org/10.1093/toxsci/kfi099